The DNA methylome is a rich source of information about human disease. Adela’s genome-wide methylation enrichment technology uniquely captures information efficiently from the entire methylome.
Adela’s technology distinguishes the most-highly informative (methylated) regions of the genome from non-informative regions and preferentially targets those regions for sequencing.
In addition, Adela’s technology does not require bisulfite conversion, which is a chemical treatment that causes loss of valuable genomic material and information.
Adela's technology leverages machine learning to detect and classify underlying disease, including tissue of origin and histologic subtype.
Adela’s technology detects signals of early disease with high sensitivity through efficient mining of the entire methylome